181) A 35 year-old man with history of ulcerative colitis is seen in your office for nodular, tender skin lesions on both of his anterior legs. He was diagnosed with ulcerative colitis about 6 months ago when he first presented with severe bloody diarrhea. He was initially managed with steroids and is now, being maintained on Mesalamine. A colonoscopy at the time of diagnosis revealed pancolitis. He has no diarrhea now. There is no evidence of weight-loss. Physical examination reveals tender erythematous lesions on the anterior aspect of his bilateral lower extremities. Laboratory investigations reveal leucocytosis and elevated C-reactive protein. Which of the following is a poor prognostic factor in Inflammatory Bowel Disease?
A) Proctitis
B) Erythema nodosum
C) Albumin of 4.1 gm/dl
D) Lymphocytosis
E) Elevated ANCA (anti-neutrophilic cytoplasmic antibodies) level.
EN bad prognostic factor for UCs
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what is the correct answer? is it E ??
Erythema nodosum and Pyoderma Gangrenosum indicate poor prognosis in ulcerative colitis. Other poor prognostic features in UC are lymphopenia, pancolitis and hypoalbuminemia.
Proctitis indicate left sided involvement only , better than pancolitis. ANCA has no prognostic value
Its about the the markers so i will say ANCA LEVELS. i could be wrong but i alway go with symptoms when i judge severity of disease
I have looked and read about erythema nod and US and it just says you may see it but there is No indication of poor prognosis